One of the primary reasons for the delay in transitioning from antibodies to Aptamer is the patent holders’ monopoly on Aptamer. , where they exerted considerable control over the field. This has caused concerns for the owners of live commercial projects based on Aptamer technology as a therapeutic to contribute development for a period of time. In contrast with the technology of monoclonal where was patient. In 1975, Georges Köhler and Cesar Milstein, a senior scientist at the LMB in Cambridge, demonstrated for the first time that antibody-producing cells isolated from immunized animals could be merged with cancer cells. As Köhler and Milstein stated plainly, such cultures “may be valuable for medical and industrial use’.In the late 1970s, the monoclonal technology status turned to an entrepreneurial attitude in Brtish life science. This was due to the aftermath of what happened concerning the right of unjustly stolen patents illegally transferred the patent right of monoclonal antibodies to American scientists, which represented the inability of Britain to convert research progress into commercial products at that time. Also, a time when Britain desperately needed to obtain the economic returns to finance the penicillin that had been invented in the late 1940s after World War II. On the other hand, despite the difficulty of the matter, this situation resulted in the spread of ideas, which led to the ease of developing and applying them around the world. Where the monoclonal antibodies were instrumental in the 1980s and 1990s development of the biotechnology industry. Over this long time, monoclonals technology had instituted in thousands of laboratories. As a result, aptamers have to face a formidable uphill battle to compete. Overall, The noteworthy question that If this the end of the aptamers or is this now regard as a difficult competition area.
One of the primary reasons for the delay in transitioning from antibodies to Aptamer is the patent holders’ monopoly on Aptamer. , where they exerted considerable control over the field.
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