Patient AO has a history of obesity and has recently gained 9 pounds. The patient has been diagnosed with hypertension and hyperlipidemia. Drugs currently prescribed

by | Sep 8, 2021 | Uncategorized | 0 comments

Scenario is listed with clear, concise instruction and details below. Please follow directions as listed an be sure to cover every question that is asked in the instructions. The ONE FACTOR I would like to be used in the essay is GENDER.
Patient AO has a history of obesity and has recently gained 9 pounds. The patient has been diagnosed with hypertension and hyperlipidemia. Drugs currently prescribed include the following:
Atenolol 12.5 mg daily
Doxazosin 8 mg daily
Hydralazine 10 mg qid
Sertraline 25 mg daily
Simvastatin 80 mg daily
By Day 7 of Week 2
Select one the following factors: genetics, gender, ethnicity, age, or behavior factors. Note, if you choose behavior, you need to include weight, exercise, alcohol use, illicit drug use and smoking habits. Do NOT include information on drug adherence.
Write a 2- to 3-page paper that addresses the following:
Explain how the factor you selected might influence the pharmacokinetic and pharmacodynamic processes in the patient from the case study you were assigned. Stick to ONE factor! Describe the effect of the ONE factor on PK/PD in general
Describe how changes in the processes might impact the patient’s recommended drug therapy. Be specific and provide examples. Describe the pharmacokinetics/pharmacodynamics of EACH drug in the patient’s list. Research the effect of the ONE factor you selected on EACH drug in the drug list provided as part of the patient case. You can use primary research articles and a drug reference for information
Explain how you might improve the patient’s drug therapy plan and explain why you would make these recommended improvements. Use bullet points for your recommendations. Include one bullet point for each drug. Be specific. For example:
decrease atenonol to 50mg daily because bioavailibilty…
stop hydralazine. Start ABC at XXmg because bioavailibilty…
This is a pharmacology class. When discussing a patient case, focus on the drugs. For care plans, focus on suggested changes to drug treatment including drug name, dose, directions for use, duration of treatment and time to follow-up.
Use a drug reference and primary research articles (randomized controlled trials and systematic reviews are preferred) to evaluate appropriateness, therapeutic effects and side effects of the drugs.
Acceptable Drug References include:
Facts and Comparisons
UpToDate
Epocrates
Merck Manual
Clinical Pharmacology
You can access Merck Manual at no charge through Walden Library. It covers disease states and drugs and includes links to treatment guidelines (which you will need in the weeks to come). Some drug references have a free and paid for version available. The free versions usually do not include enough information for this class.
How to access Merck Manual.docx
Speed Pharmacology and You Tube are NOT acceptable references for academic writing. They are acceptable resources for learning / increasing your understanding of a topic
Read the question carefully. Some of you provided great information in your writing, but you did not answer the question. Use the guidance provided in the announcement on Monday of each week
Use generic names for drugs. The brand name can be included in parenthesis – e.g. furosemide (Lasix®)
References should fit the patient e.g.
an article on metformin use in oncology patients can only be cited if your patient is taking metformin and has cancer. In addition, the type of cancer and cancer treatments used in the research and in your patient should match
an article on pharmacokinetics in a diabetic patient taking metformin can only be used if your patient has diabetes and is on metformin.
To Prepare
Review the Resources for this module and consider the impact of potential pharmacotherapeutics for cardiovascular disorders introduced in the media piece.
Review the case study assigned by your Instructor for this Assignment.
Select one the following factors: genetics, gender, ethnicity, age, or behavior factors.
Reflect on how the factor you selected might influence the patient’s pharmacokinetic and pharmacodynamic processes.
Consider how changes in the pharmacokinetic and pharmacodynamic processes might impact the patient’s recommended drug therapy.
Think about how you might improve the patient’s drug therapy plan based on the pharmacokinetic and pharmacodynamic changes. Reflect on whether you would modify the current drug treatment or provide an alternative treatment option for the patient.
Please use the listed reference below as well as any other scholarly resources for this assignment.
Rosenthal, L. D., & Burchum, J. R. (2021). Lehne’s pharmacotherapeutics for advanced practice nurses and physician assistants (2nd ed.) St. Louis, MO: Elsevier.
Chapter 33, “Review of Hemodynamics” (pp. 285–289)
Chapter 37, “Diuretics” (pp. 290–296)
Chapter 38, “Drugs Acting on the Renin-Angiotensin-Aldosterone System” (pp. 297–307)
Chapter 39, “Calcium Channel Blockers” (pp. 308–312)
Chapter 40, “Vasodilators” (pp. 313–317)
Chapter 41, “Drugs for Hypertension” (pp. 316–324)
Chapter 42, “Drugs for Heart Failure” (pp. 325–336)
Chapter 43, “Antidysrhythmic Drugs” (pp. 337–348)
Chapter 44, “Prophylaxis of Atherosclerotic Cardiovascular Disease: Drugs That Help Normalize Cholesterol and Triglyceride Levels” (pp. 349–363)
Chapter 45, “Drugs for Angina Pectoris” (pp. 364–371)
Chapter 46, “Anticoagulant and Antiplatelet Drugs” (pp. 372–388)
Rubric Detail
Select Grid View or List View to change the rubric’s layout.
Name: NURS_6521_Week2_Assignment_Rubric
Grid View
List View
Excellent Good Fair Poor
Explain how the factor you selected might influence the pharmacokinetic and pharmacodynamic processes in the patient from the case study you were assigned.
23 (23%) – 25 (25%)
The response accurately and completely explains in detail how the factor selected might influence the pharmacokinetic and pharmacodynamic processes in the patient.
20 (20%) – 22 (22%)
The response provides a basic explanation of how the factor selected might influence the pharmacokinetic and pharmacodynamic processes in the patient.
18 (18%) – 19 (19%)
The response inaccurately or vaguely explains how the factor selected might influence the pharmacokinetic and pharmacodynamic processes in the patient.
0 (0%) – 17 (17%)
The response inaccurately and vaguely explains how the factor selected might influence the pharmacokinetic and pharmacodynamic processes in the patient, or is missing.
Describe how changes in the processes might impact the patient’s recommended drug therapy. Be specific and provide examples.
27 (27%) – 30 (30%)
The response accurately and completely describes in detail how changes in the processes might impact the patient’s recommended drug therapy.
Accurate, complete, and aligned examples are provided to support the response.
24 (24%) – 26 (26%)
The response accurately describes how changes in the processes might impact the patient’s recommended drug therapy.
Accurate examples may be provided to support the response.
21 (21%) – 23 (23%)
The response inaccurately or vaguely describes how changes in the processes might impact the patient’s recommended drug therapy.
Inaccurate or vague examples are provided to support the response.
0 (0%) – 20 (20%)
The response inaccurately and vaguely describes how changes in the processes might impact the patient’s recommended drug therapy, or is missing.
Inaccurate and vague examples may be provided to support the response, or is missing.
Explain how you might improve the patient’s drug therapy plan, and explain why you would make these recommended improvements.
27 (27%) – 30 (30%)
The response accurately and clearly explains in detail how to improve the patient’s drug therapy plan.
The response includes an accurate and detailed explanation to support the recommended improvements.
24 (24%) – 26 (26%)
The response accurately explains how to improve the patient’s drug therapy plan.
The response may include an accurate explanation to support the recommended improvements.
21 (21%) – 23 (23%)
The response inaccurately or vaguely explains how to improve the patient’s drug therapy plan.
The response may include an inaccurate, vague, or misaligned explanation to support the recommended improvements.
0 (0%) – 20 (20%)
The response inaccurately and vaguely explains how to improve the patient’s drug therapy plan, or is missing.
The response may include an inaccurate and vague explanation to support the recommended improvements, or is missing.
Written Expression and Formatting – Paragraph Development and Organization:
Paragraphs make clear points that support well developed ideas, flow logically, and demonstrate continuity of ideas. Sentences are carefully focused–neither long and rambling nor short and lacking substance.
5 (5%) – 5 (5%)
Paragraphs and sentences follow writing standards for flow, continuity, and clarity.
4 (4%) – 4 (4%)
Paragraphs and sentences follow writing standards for flow, continuity, and clarity 80% of the time.
3.5 (3.5%) – 3.5 (3.5%)
Paragraphs and sentences follow writing standards for flow, continuity, and clarity 60%–79% of the time.
0 (0%) – 3 (3%)
Paragraphs and sentences follow writing standards for flow, continuity, and clarity less than 60% of the time.
Written Expression and Formatting – English writing standards:
Correct grammar, mechanics, and proper punctuation
5 (5%) – 5 (5%)
Uses correct grammar, spelling, and punctuation with no errors
4 (4%) – 4 (4%)
Contains a few (1–2) grammar, spelling, and punctuation errors
3.5 (3.5%) – 3.5 (3.5%)
Contains several (3–4) grammar, spelling, and punctuation errors
0 (0%) – 3 (3%)
Contains many (≥ 5) grammar, spelling, and punctuation errors that interfere with the reader’s understanding
Written Expression and Formatting – The paper follows correct APA format for title page, headings, font, spacing, margins, indentations, page numbers, running head, parenthetical/in-text citations, and reference list.
5 (5%) – 5 (5%)
Uses correct APA format with no errors
4 (4%) – 4 (4%)
Contains a few (1–2) APA format errors
3.5 (3.5%) – 3.5 (3.5%)
Contains several (3–4) APA format errors
0 (0%) – 3 (3%)
Contains many (≥ 5) APA format errors
Total Points: 100
Name: NURS_6521_Week2_Assignment_Rubric

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